Common symptoms
Fatigue
Persistent low energy and tiredness not explained by other causes
Low libido
Significant decrease in interest in sexual activity
Mood changes
Irritability, depression, or difficulty concentrating
Reduced muscle mass
Loss of muscle strength and mass despite regular activity
Weight gain
Increased body fat, particularly around the abdomen
Erectile dysfunction
Difficulty achieving or maintaining erections due to hormonal deficiency
Testosterone levels naturally decline with age, but hypogonadism refers to levels that are clinically low and causing symptoms. It can be caused by testicular injury, pituitary disorders, obesity, or chronic illness. Blood testing is required to confirm the diagnosis.
Testosterone replacement therapy (TRT) can improve energy, libido, mood, and muscle mass within weeks to months. Ongoing monitoring of testosterone levels, hematocrit, and prostate health is required throughout treatment.